Immersed-boundary-type models of intravascular platelet aggregation
نویسندگان
چکیده
منابع مشابه
Immersed-Boundary-Type Models of Intravascular Platelet Aggregation ⋆
The formation of platelet aggregates during blood clotting is modeled on two scales using ideas motivated by Peskin’s Immersed Boundary Method. The microscopic scale models track individual platelets, their mechanical interactions with one another and the surrounding fluid, their detection of and response to chemical activators, and the formation of cohesive and adhesive ‘links’ between platele...
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The formation of platelet aggregates during blood clotting is modeled on two scales using ideas motivated by Peskin’s immersed boundary method. The microscopic scale models track individual platelets, their mechanical interactions with one another and the surrounding fluid, their detection of and response to chemical activators, and the formation of cohesive and adhesive ‘links’ between platele...
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Aggregated platelets and occlusive platelet thrombi were found in small myocardial vessels of dogs on electron-microscope examination after prolonged infusion of norepinephrine. The etiology of the myocardial necrosis and fibrosis induced by catecholamines in experimental animals and seen in patients with pheochromocytoma and patients after norepinephrine treatment for shock may be related to t...
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Mathematical models of valveless pumping can be represented by either a closed loop system or an open tube system. In this paper, we present a three-dimensional model of valveless pumping in a closed loop system. We also present a two-dimensional model using an open elastic cylinder contained in a rigid tank. In both models, we take the periodic compress-and-release action at the asymmetric loc...
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The term “immersed boundary method” was first used in reference to a method developed by Peskin (1972) to simulate cardiac mechanics and associated blood flow. The distinguishing feature of this method was that the entire simulation was carried out on a Cartesian grid, which did not conform to the geometry of the heart, and a novel procedure was formulated for imposing the effect of the immerse...
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ژورنال
عنوان ژورنال: Computer Methods in Applied Mechanics and Engineering
سال: 2008
ISSN: 0045-7825
DOI: 10.1016/j.cma.2007.06.030